The CompPlus is one of the most complete, accurate and advanced hormone profiles for both men and women. This test is the “Gold Standard” for balancing male and female sex hormones, adrenal and thyroid hormones. It also includes the 2/16α EQ (estrogen quotient) ratio, an important and modifiable predictor of hormone-related cancer risk.
Why is 24-hour urine testing the “Gold Standard” of hormone evaluation? Sex hormones are released in “pulsed doses” throughout the 24-hour period. Single blood tests can be high or low depending on where in this cycle they occur. They are the least accurate of hormone tests. Saliva is the next best, because saliva represents some degree of “averaging” of the total sex hormones. However, various physical conditions can alter the concentration of hormones in saliva and decrease the accuracy of the test. 24-hour urine testing collects the “peaks and valleys” of hormone release and averages it. This gives an extremely accurate profile of the daily amount of hormones release.
This test also looks at adrenal hormones (which factor into sex hormone production because the adrenals make sex hormones) and the estrogen quotient, a potent risk factor (that can be modified) for hormone-related cancers.
Using a 24-hour urine specimen, the CompPlus evaluates the following:
Estrogens – estrone, estradiol, estriol, 2-hydroxyestrone, 16α-hydroxyestrone, 4-hydroxyestrone, 2-methoxyestrone, 2-methoxyestradiol,
Progesterone – pregnanediol (progesterone metabolite),
Androgens – DHEA, testosterone,
5α -androstanediol, 5β-androstanediol, androsterone, eticholanolone, cortisone, cortisol,
Glucocorticoids (adrenal hormones) pregnanetriol, tetrahydrocortisone, allo-tetrahydrocortisol, tetraqhydrocortisol, 11β-hydroxyandrosterone, 11β-hydroxyetiocholanolone,
Mineralocorticoids (adrenal hormones) aldosterone, allo-tetrahydrocorticosterone, tetrahydrocorticosterone, 11-dehydrotetrahydrocorticosterone,
Thyroid hormones – free T3, free T4
EQ– 2/16α estrogen quotient (EQ) ratio
One of the most important tests for anti-aging, longevity and cancer prevention protocols.Also the best test for female menopause / male andropause – related symptoms.