Strontium, a naturally occurring mineral in the same
mineral family as calcium and magnesium, has been shown to promote bone growth
in both human and animal studies. Strontium occurs in nature in soil, foods, and
bones.
Before you get nervous, let's clarify something: this is
NOT the radioactive "strontium 90" that many of us were forced to hide from
under our desks in the 1950s during "A-bomb drills." The strontium I'm talking
about is an all-natural, non-radioactive mineral that is quite safe.
Strontium has been studied since the early 1900's for
its effect on bone density. Strontium and calcium have been shown to be superior
to calcium alone for rebuilding bone.
A Mayo Clinic study conducted in 1959 looked at 22
individuals with severe (and painful) osteoporosis. Part of the group took 1,700
milligrams of strontium daily. Another group took the same amount of strontium
with estrogen and testosterone. In the "hormones plus strontium" group, 9 of 10
people experienced marked improvement of their symptoms, and the other one had
moderate improvement. In the strontium-only group, 18 of 22 had marked
improvement and the other four had moderate improvement. Bottom line:
every person in this study had
moderated to marked improvement using strontium.
Another study in 1979, performed on a group of patients
with metastatic bone cancer (cancer that has spread to bone), showed an
improvement in bone density and decreased bone pain in the strontium-treated
group.
In 1985, another study found that "Following strontium
therapy, all [measurements] of bone formation increased, while bone resorption
remained unchanged." Sixteen years later, a research group reviewed the studies
on strontium and concluded that "In addition to its anti-resorptive activity,
strontium was found to have anabolic (tissue-building) activity in bone."
These studies have used strontium carbonate, strontium
lactate and strontium gluconate. All forms of strontium have produced positive
effects, indicating that it is the strontium itself that is active and not what
it is bound to. Why do I mention this little "factoid?" So that Big Pharma can't
fool you into buying an expensive drug form of strontium when a simple
supplemental form works as well.
Naturally, the most recent strontium-osteoporosis
research has been performed by a drug company using a patentable
strontium combination. (Remember, strontium by itself isn't patentable because
it is a naturally-occurring substance). But combined with a synthetic substance
called ranelic acid, strontium becomes a patentable drug. This "drug" is
available in Europe as the trademarked Protos®, but all
studies before this suggest that it is the strontium itself which is responsible
for bone-building effects.
In a three-year, randomized, double-blind, placebo
controlled study using 680 milligrams of strontium daily, women suffering from
osteoporosis had a 41 percent
reduction vertebral fractures compared with placebo. The overall
vertebrae density in the strontium group increased by 11.4 percent compared to a
1.3 percent decrease in the placebo group.
In another recent study, 353 women who had already
experienced at least one osteoporosis-related vertebral fracture took varying
levels of strontium ranelate or a placebo. In the group who tool 680 milligrams
of strontium daily, there was a 3%
increase in lumbar bone mineral density per year, significantly
greater than placebo. At the end of the second year of the study, there was a
significant decrease in fractures in the strontium group compared to placebo.
In a 2002 randomized, double-blind, placebo-controlled
trial, 160 post-menopausal females who did not have osteoporosis were asked to
take placebo or varying amounts of strontium daily. Compared to the placebo
group, women who took 340 milligrams strontium a day had a
significant increase in bone mineral
density in two years' time. All groups also took 500 milligrams of
calcium daily, but no hormones or vitamin D.
It appears that not only can strontium prevent
osteoporosis, it can repair existing damage. And it doesn't seem to
matter what form it is in: strontium ranelate (a patented drug in Europe),
strontium gluconate, strontium lactate, or strontium carbonate. It's the mineral
strontium itself that works the magic on bone!
Sources of Strontium
Bad news: there's not enough strontium in food to have a significant effect if
you already have osteoporosis. If you have a diagnosis of osteoporosis, you
should take strontium in supplement form. If you don't currently have
osteoporosis, then eating plenty of food high in strontium "may" be enough to
protect you. Foods high in strontium include spices, seafood, whole grains, root
and leafy vegetables, and legumes.
If you want to be on the safe side concerning
osteoporosis prevention, consider taking one dose of strontium (200-400mg) per
day. For those without osteoporosis but with known risk factors (family history,
immobility, smoking, etc.) one capsule twice daily is prudent. Also be sure to
take the recommended calcium (1,200-1,500 milligrams for post-menopausal
females) plus associated bone nutrients including magnesium, zinc, boron and
vitamin D.
NOTE: Maxi Multi does not contain strontium. If you see
a "bone formula" with strontium, don't take it. Strontium should be taken away
from calcium and magnesium for best absorption.
Suggested dose: 1 capsule, 1-2 times per day with or between meals
(take seperately from calcium). One capsule per day is advised for
prevention, 2 caps per day for those at high risk of osteoporosis or in
already-established cases of osteoporosis.
Each (one) capsule contains:
Strontium carbonate 340 mg
Product # 287 (60 Capsules) $24.95
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References
(To view, roll mouse over the "References" heading; to hide, click on the heading)
1.) Strontium Ranelate Reduces the Risk of Nonvertebral Fractures in
Postmenopausal Women with Osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS)
Study. J Clin Endocrinol Metab. 2005 May; 90(5):2816-22. Epub 2005 Feb 22.
2.) Picking a bone with contemporary osteoporosis management: Nutrient
strategies to enhance skeletal integrity. Clinical Nutrition (Epub ahead of
print, 2006 October 12).
3.) The effects of strontium ranelate on the risk of vertebral fracture in women
with postmenopausal osteoporosis.” New England Journal of Medicine 350
(2004):459 - 68.
4.) Strontium ranelate reduces the risk of nonvertebral fractures in
postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS)
study. Journal of Clinical Endocrinology and Metabolism 90 (2005):2816 - 22.
5.) Strontium in Finnish foods. International Journal for Vitamin and Nutrition
Research 52 (1982): 342 - 50.
6.) Gaby AR. Preventing and Reversing Osteoporosis. Rocklin, CA: Prima
Publishing, 1994, 85–92 [review].
7.) Strontium ranelate: a dual mode of action rebalancing bone turnover in
favour of bone formation. Curr Opin Rheumatol. 2006 Jun;18 Suppl 1:S11-5.